Antisense Oligos                               Â
http://www.biosyn.com/bioconjugation.aspx
The use of antisense oligonucleotides(ASOs) was first identified over twenty years ago as a method to arrest gene expression levels both in vitro and in vivo where single-stranded DNA or RNA in antisense configuration can target a specific sense mRNA. The strategies in the design and chemistry of antisense compounds have become an effective tool in molecular biology basic research, genomics, proteomics, target screening/validation and drug discovery.
http://www.biosyn.com/bioconjugation.aspx
The use of antisense oligonucleotides(ASOs) was first identified over twenty years ago as a method to arrest gene expression levels both in vitro and in vivo where single-stranded DNA or RNA in antisense configuration can target a specific sense mRNA. The strategies in the design and chemistry of antisense compounds have become an effective tool in molecular biology basic research, genomics, proteomics, target screening/validation and drug discovery.